Nalossone [Dcit]
Brand names,
Nalossone [Dcit]
Analogs
Nalossone [Dcit]
Brand Names Mixture
Nalossone [Dcit]
Chemical_Formula
C19H21NO4
Nalossone [Dcit]
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Nalossone [Dcit]
fda sheet
Nalossone [Dcit]
msds (material safety sheet)
Nalossone [Dcit]
Synthesis Reference
No information avaliable
Nalossone [Dcit]
Molecular Weight
327.374 g/mol
Nalossone [Dcit]
Melting Point
200 - 205 oC
Nalossone [Dcit]
H2O Solubility
Soluble
Nalossone [Dcit]
State
Solid
Nalossone [Dcit]
LogP
1.464
Nalossone [Dcit]
Dosage Forms
Liquid
Nalossone [Dcit]
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Nalossone [Dcit]
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Nalossone [Dcit]
Absorption
Well absorbed following intramuscular injection.
Nalossone [Dcit]
side effects and Toxicity
No information avaliable
Nalossone [Dcit]
Patient Information
No information avaliable
Nalossone [Dcit]
Organisms Affected
Humans and other mammals